Figure 3
From: Role of acid-sensing ion channel 3 in sub-acute-phase inflammation
Paw edema following the induction of inflammation. Measurement of thickness of ipsilateral paws swelled with inflammation by both complete Freund's adjuvant (CFA) and carrageenan. A, Thickness 4 h after intraplantar injection. B, Thickness 2 days after injection. C, Thickness 7 days after injection. WT: ASIC3+/+ mice, n = 6 in each group. KO: ASIC3-/- mice, n = 6 in each group. *p < 0.05, **p < 0.01, ***p < 0.001 compared with the saline control group. #p < 0.05, ##p < 0.01, ###p < 0.001 comparison between CFA and carrageenan in the same genotype group.