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Figure 7 | Molecular Pain

Figure 7

From: Peripheral nerve injury sensitizes neonatal dorsal horn neurons to tumor necrosis factor-α

Figure 7

Peripheral nerve injury elevates TNFα levels in the adult, but not neonatal, dorsal horn. (A) The concentration of TNFα (normalized to sham-operated controls) in the ipsilateral dorsal horn was not significantly altered during the first seven postoperative days (POD) following SNI at P6 (p = 0.276; two-way ANOVA). (B) In contrast, adult SNI significantly increased TNFα levels in the ipsilateral dorsal horn over the same postoperative period (*p = 0.045; two-way ANOVA).

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