Figure 3
From: Characterization of NF-kB-mediated inhibition of catechol-O-methyltransferase
TNFα-mediated repression of COMT is attenuated in H4 IκBα-SR astroglial cells. Administration of TNFα (100 ng/ml) does not reduce COMT expression in H4 IκBα-SR cells as indicated by (A) a representative Western blot, (B) quantitative analysis of Western blots from experiments performed in triplicate, and (C) quantitative real-time RT-PCR analysis of MB-COMT mRNA. P > 0.05 different from untreated control.