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Table 2 A comparison of dorsal horn neuronal responses evoked using electrical and natural stimuli in PSNL and sham mice

From: Behavioural and electrophysiological characterisation of experimentally induced osteoarthritis and neuropathy in C57Bl/6 mice

 

PSNL

Sham

A-fibre threshold (mA)

0.31 ± 0.07

0.27 ± 0.04

C-fibre threshold (mA)

0.77 ± 0.15

1.1 ± 0.21

A-fibre response (AP)

100 ± 11

89 ± 11

C-fibre response (AP)

166 ± 24*

101 ± 10

Post discharge (AP)

144 ± 30

99 ± 15

Input (AP)

211 ± 38

165 ± 29

Wind-up (AP)

104 ± 18

63 ± 12

   Hill slope

24.8 ± 4.4*

15.1 ± 1.5

Brush (AP)

94 ± 21

67 ± 17

Pinch (AP)

237 ± 46**

80 ± 10

Acetone (AP)

18 ± 7

9 ± 3

1°C

77 ± 33

31 ± 15

Spontaneous (Hz)

3.4 ± 1.3

1.3 ± 0.8

  1. Data are presented as mean ± S.E.M. for dorsal horn neurones recorded in PSNL (n = 13) and sham mice (n = 12). AP represents the mean number of action potentials in response to either a peripheral electrical or 10 s natural stimulus. * p < 0.05; ** p < 0.01.
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Molecular Pain

ISSN: 1744-8069

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