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Figure 4 | Molecular Pain

Figure 4

From: Glycine receptor in rat hippocampal and spinal cord neurons as a molecular target for rapid actions of 17-β-estradiol

Figure 4

Inhibitory effect of E 2 on recombinant GlyRs. (A) Sample traces demonstrating the effects of 10 μM E2 on various homomeric and heteromeric GlyRs. (B) Summary of results from all experiments similar to those shown in A. E2 selectively inhibited the peak amplitude of I Gly mediated by α2-containing GlyRs and α3β heteromeric GlyR. Each column represents the average value of 6–11 neurons. ***P < 0.001, Paired Student's t-test, compared with the control without E2 treatment (dashed line).

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Molecular Pain

ISSN: 1744-8069

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