Figure 5
From: Antidepressants inhibit P2X4 receptor function: a possible involvement in neuropathic pain relief
Effect of intrathecal administration of fluvoxamine and citalopram on the decrease in the PWT after nerve injury. A significant antiallodynic effect was observed following intrathecal administration of 10 nmol fluvoxamine at day 7 after nerve injury (a). (**p < 0.01 and *p < 0.05; fluvoxamine 10 nmol vs. control by a Mann-Whitney U-test.) No significant change was observed following administration of 10 nmol citalopram (b). (p > 0.05 by a Mann-Whitney U-test.) Data are means ± SEM of 5–10 rats.