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Figure 1 | Molecular Pain

Figure 1

From: Cannabinoid receptor type 2 activation induces a microglial anti-inflammatory phenotype and reduces migration via MKP induction and ERK dephosphorylation

Figure 1

Effects of microglial CBR2 activation on the MKP-1/3 pathway. Representative western blots and quantification of MKP-1 (A) and MKP-3 expression (B) at different incubation time points (15–60 min, 0 = medium control group) in LPS-stimulated microglia in the presence or absence of JWH015 (1 μM). JWH015 produced a MKP-1 and MKP-3 increase (15 min). +p < 0.05 vs. medium control group; *p < 0.05 vs. LPS alone group.

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