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Figure 2 | Molecular Pain

Figure 2

From: Behavioral phenotypes of mice lacking purinergic P2X4 receptors in acute and chronic pain assays

Figure 2

Reduction in the amount of peripheral inflammation-induced pain in p2rx4-/- mice. (A) Paw withdrawal thresholds (left panel, ipsilateral hindpaw; right panel, contralateral hindpaw) of wild-type (n = 8) and p2rx4-/- mice (n = 8) before (0) and 1, 3, 7, 10 and 14 days after intraplantar injection of CFA (0.01 mg/20 μL). *p < 0.05, **p < 0.01, ***p < 0.001 vs. wild-type mice. (B) Change in the weight (g) of the ipsilateral and contralateral hindpa0w 14 days after the injection of CFA (wild-type, n = 6; p2rx4-/-, n = 6). *p < 0.05 vs. wild-type mice. All data are presented as means ± SEM.

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