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Figure 2 | Molecular Pain

Figure 2

From: An in vivo mouse model of long-term potentiation at synapses between primary afferent C-fibers and spinal dorsal horn neurons: essential role of EphB1 receptor

Figure 2

LTP of synapses between C-fibers and DH neurons in mice in vivo. LTP training protocol in A-C: 100 Hz, 5 × threshold currents, 0.5 ms, 100 pulses, 4 trains of 1-s duration at 10-s intervals. Examples of the C-fiber-evoked field potentials given in each figure were recorded before (a) and after (b) tetanic stimulation (indicated by the arrow in each figure) alone (A) or combined with MK-801 with pre-treatment (B) and post-treatment (C), respectively. The nonparametric Wilcoxon signed-rank test and the Kruskal-Wallis test were used to test the field potential within and between the groups, respectively (p < 0.01 in A and C; p > 0.05 in B; p < 0.01 between A/B and B/C; p > 0.05 between A/C).

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Molecular Pain

ISSN: 1744-8069

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