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Figure 7 | Molecular Pain

Figure 7

From: An in vivo mouse model of long-term potentiation at synapses between primary afferent C-fibers and spinal dorsal horn neurons: essential role of EphB1 receptor

Figure 7

Effects of EphB2-Fc and targeted mutation of EphB1 receptor on expression of c-Fos in the mouse DH following HFS in vivo. Examples of Fos-immunoreactive neurons are given in A (wild type mice, WT) and B (EphB1 receptor protein-null mice, EphB-/-) and data summarized in C. Five groups of mice (n = 5 each group) were tested and examined, the sham groups received no HFS (A and B) and the other groups received HFS with pretreatment of IgG-Fc or EphB2-Fc (A) HFS alone (B). * p < 0.05, ** p < 0.01 indicates significant differences compared with the WT-Sham. ## p < 0.01 indicate significant difference compared with WT-HFS-IgG-Fc (as control). &p < 0.05 indicate significant difference compared with EphB1-/--Sham.

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Molecular Pain

ISSN: 1744-8069

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