Variable | OPRM 118 genotypes | p value | ||
---|---|---|---|---|
AA | AG | GG | ||
Age (years) | 32.4 (4.7) | 32.0 (4.8) | 32.7 (5.4) | 0.19 |
Height (cm) | 157.7 (5.6) | 157.5 (5.8) | 157.6 (5.4) | 0.88 |
Weight (kg) | 70.2 (10.5) | 70.9 (11.3) | 72.4 (11.6) | 0.11 |
BMI (kg/m2) | 28.2 (4.1) | 28.6 (4.4) | 29.2 (4.5) | 6.0 × 10-5 |
Duration of operation (min) | 53.3 (16.3) | 54.1 (15.9) | 54.0 (15.0) | 0.78 |
Morphine* (total) | 4.0 (3.5) | 6.0 (5.5) | 7.0 (7.0) | 1.7 × 10-5 |
100 × Morphine/kg bodyweight * | 5.8 (5.7) | 8.8 (8.2) | 10.9 (10.3) | 6.6 × 10-5 |
VAS score* (time averaged) | 0.29 (0.29) | 0.43 (0.36) | 0.43 (0.36) | 2.5 × 10-2 |
VAS score* (average of maximum) | 1.0 (0.5) | 2.0 (0.5) | 2.0 (1.0) | 0.19 |