Figure 4

Linear Discriminant Analysis (LDA). (a) The figure depicts 2 metabolite ratios (e.g., NAAG/Cr and Glu/Cr) that separate controls from migraineurs through the black line in the cingulate. (b) Similar data is shown for the insula. (c) and (d) show a bootstrap calculation for assessment of statistical accuracy of the estimated LDA coefficients for the ACC and insula, respectively.