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Table 1 Levels of endocannabinoids and related fatty acid ethanolamides measured in the ipsilateral and contralateral spinal cord of spinal nerve ligated (SNL) rats treated chronically with vehicle (sterile water, ip, 2 ml/kg) daily for 14 days.

From: Minocycline treatment inhibits microglial activation and alters spinal levels of endocannabinoids in a rat model of neuropathic pain

  

AEA (pmol/g)

2-AG (nmol/g)

OEA (nmol/g)

PEA (nmol/g)

SNL – vehicle

Ipsilateral

65.86 ± 6.92**

52.21 ± 4.47

1.72 ± 0.15

4.20 ± 0.39**

 

Contralateral

28.42 ± 0.86

54.40 ± 4.02

1.43 ± 0.08

8.80 ± 0.97

  1. Data were analysed using Mann-Whitney non-parametric tests and are expressed as mean ± SEM mol/g (n = 5–6 rats per group). ** P < 0.01 vs contralateral spinal cord. AEA, anandamide; 2-AG, 2-arachidonoylglycerol; PEA, N-palmitoylethanolamine; OEA, N-oleoylethanolamine.