Figure 5

C- fos -like immunoreactivity at the L4-L5 spinal segment ipsilateral to the hindpaw injection of formalin in ipsilateral lumbar sections of the dorsal horn of the spinal cord. Three different situations are represented (all animals were injected with formalin): control rats that received saline (a) and rat receiving either JMV-431 (b) or levocabastine (c). Note that both JMV-431 and levocabastine reduced the level of formalin-evoked c-fos expression in the superficial dorsal horn. Scale bar: 200 μm.