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Figure 3 | Molecular Pain

Figure 3

From: Expression and function of proton-sensing G-protein-coupled receptors in inflammatory pain

Figure 3

Mechanical and thermal hyperalgesia in mice after CFA-induced peripheral inflammation. The wild-type CD1 mice (12 week-old) were injected with 25 μl CFA (50% in saline, A, C), or saline (B, D). The threshold (A, B) and the latency (C, D) of paw withdrawal were measured before injection (t = 0) and after injection (t = 4, 24, and 72 hours). All data are mean ± SEM of total tested mice (n = 6 per group). Comparison between inflammatory agent-injected and saline-injected animals (#) or between contralateral side and ipsilateral side of agent-injected animals (*) was by t test. *#p < 0.05, **##p < 0.01, ***###p < 0.001.

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