Figure 3

Time-dependent increase of PGE2 release from rat trigeminal satellite cells. Cells were incubated with or without tested stimuli 10 ng/ml IL-1β (A) or 100 μM DETA/NO (B). PGE2 secretion was evaluated at different time points by RIA (up to 24 h for IL-1β). Data are expressed as pg/ml of PGE2, and are means ± SEM of n = 6 replicates for each experimental group. *** p < 0.001 vs. control (two-way ANOVA followed by Bonferroni's post-hoc test).