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Figure 5 | Molecular Pain

Figure 5

From: Proinflammatory-activated trigeminal satellite cells promote neuronal sensitization: relevance for migraine pathology

Figure 5

IL-1β and DETA/NO differentially induce COX1 and COX2 expression in rat trigeminal satellite cells. Satellite cells were incubated with 10 ng/ml IL-1β (A and B) or 100 μM DETA/NO (C and D) for the indicated times, then total RNA was extracted. Expression of COX2 (A and C) or COX1 (B and D) was evaluated by real-time (Q) RT-PCR using the comparative quantitation analysis. Data are expressed as the signal of mRNA from treated cultures relative to that from untreated controls (± SEM; n = 3); data were compiled from two independent experiments. ** p < 0.01, *** p < 0.001 vs. controls.

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