Figure 5From: The endogenous hydrogen sulfide producing enzyme cystathionine-β synthase contributes to visceral hypersensitivity in a rat model of irritable bowel syndrome Effect of CBS inhibitor on AWR (abdominal withdrawal reflex) in response to colorectal distention (CRD). (A) Neonatal AA-treatment significantly enhanced the AWR scores. *p < 0.05 compared with controls. (B) CBS inhibitor hydroxylamine (HA, 25 μmol/Kg body weight) significantly attenuated the AWR scores in neonatal AA-treated rats. *p < 0.05 compared with Pre-HA. (C) HA did not produce any effect on AWR scores in healthy control rats.Back to article page