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Figure 2 | Molecular Pain

Figure 2

From: Descending serotonergic facilitation and the antinociceptive effects of pregabalin in a rat model of osteoarthritic pain

Figure 2

Electrophysiological recordings of deep dorsal horn wide dynamic range neuronal responses in MIA (n = 30) and sham rats (n = 34). A) Mean evoked neuronal response of peripheral mechanical stimulation during the 10 second application period. B) Mean after-discharge response of neurons to mechanical stimulation. C) Mean evoked neuronal response of peripheral thermal stimulation during the 10 second application period D. Mean after-discharge response of neurons to thermal stimulation. MIA injection resulted in an overall increase in neuronal excitability. * p < 0.05 compared with sham control data.

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Molecular Pain

ISSN: 1744-8069

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