Skip to main content
Figure 3 | Molecular Pain

Figure 3

From: Descending serotonergic facilitation and the antinociceptive effects of pregabalin in a rat model of osteoarthritic pain

Figure 3

Comparison of the effects of spinal administration of ondansetron on the evoked neuronal responses to dynamic brush and mechanical punctate stimulation in sham (n = 8) and MIA (n = 8) rats. The neuronal responses evoked by dynamic brush, von Frey 2 and 8 g stimulation were significantly reduced by 50 and 100 μg of ondansetron in the MIA group. Ondansetron produced no significant effects on the mechanical evoked neuronal responses in the sham group. *p < 0.05 compared with pre- drug baseline control data.

Back to article page