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Figure 4 | Molecular Pain

Figure 4

From: Descending serotonergic facilitation and the antinociceptive effects of pregabalin in a rat model of osteoarthritic pain

Figure 4

Effects of spinal administration of ondansetron on the evoked neuronal responses to thermal stimulation of the peripheral receptive field area in sham (n = 8) and MIA (n = 8) rats. Ondansetron at 5 μg produced a greater inhibition of the evoked response to 45°C in the MIA group compared with the control group; the effects of the drug on the other thermal stimuli tested were not different between groups. Data are expressed as the mean percentage of pre-drug control values ± S.E.M. *p < 0.05 **p < 0.01 compared with pre- drug baseline control data. §p < 0.05 compared with sham control group.

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Molecular Pain

ISSN: 1744-8069

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