Skip to main content

Table 1 A comparison of the baseline electrophysiological responses of deep dorsal horn neurons in saline (n = 30) and MIA (n = 34) injected rats.

From: Descending serotonergic facilitation and the antinociceptive effects of pregabalin in a rat model of osteoarthritic pain

  

Sham (n = 30)

MIA (n = 34)

 

Depth (μm)

787 ± 50

730 ± 37

Electrically-evoked Responses

C-fibre threshold (mA)

0.76 ± 0.08

0.71 ± 0.07

 

Aβ-fibre evoked response (AP)

157 ± 14

175 ± 13

 

Aδ-fibre evoked response (AP)

136 ± 13

137 ± 12

 

C-fibre evoked response (AP)

401 ± 31

475 ± 38

 

Post discharge (AP)

257 ± 37

265 ± 34

 

Input (AP)

334 ± 52

389 ± 37

 

Wind-up (AP)

442 ± 58

452 ± 60

  1. The electrical evoked responses are expressed as the mean number of action potentials (AP) ± S.E.M. evoked by a train of 16 electrical stimuli given at three times the threshold for C-fibre evoked neuronal response.