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Figure 7 | Molecular Pain

Figure 7

From: Roles of the AMPA receptor subunit GluA1 but not GluA2 in synaptic potentiation and activation of ERK in the anterior cingulate cortex

Figure 7

ERK phosphorylation as an indicator of synaptic plasticity in the ACC in mouse models of inflammatory pain. (A) Typical examples of increase in immunoreactivity for phospho-ERK1/2 in ACC of WT mice at 10 minutes (min) following intraplantar (ipl.) injection of formalin or 30 min following intraplantar injection of complete Freund's adjuvant (CFA). (B) Analysis of the time-course and quantification of nociceptive activity-induced ERK phosphorylation in ACC via densitometric analysis of immunostained sections.

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