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Table 3 Differential effects of 35 μM wortmannin treatment on P2X3 current rundown (%) in DRG neurons and recombinant expression systems.

From: Subtype-specific regulation of P2X3 and P2X2/3 receptors by phosphoinositides in peripheral nociceptors

 

Control

Wortmannin

DRG neurons

96.0 ± 7.5

92.0 ± 5.3

HEK293 cells

89.9 ± 6.6

59.8 ± 5.4 **

Xenopus oocytes

93.1 ± 4.9

62.6 ± 7.0 **

  1. ** P < 0.01
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Molecular Pain

ISSN: 1744-8069

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