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Figure 3 | Molecular Pain

Figure 3

From: Tumor necrosis factor-alpha (TNF-α) enhances functional thermal and chemical responses of TRP cation channels in human synoviocytes

Figure 3

Response of SW982 synoviocytes to "moderate" temperature increase. Response of SW982 synoviocytes [Ca2+]i to "moderate" (30 and 36°C) temperature increase in the presence (+) or absence (-) of 2-AB. The 30 or 36°C solution was applied for 8 minutes. (A) Representative calcium trace shows lack of effect of 2-AB applied after 5 minutes of thermal stimulation. (B) In the treated groups, 2-AB was applied in the perfusion 5–10 minutes before and during thermal stimulation. Peak (left) and average (right) calcium response (n = 4 trials for each group).

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Molecular Pain

ISSN: 1744-8069

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