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Figure 4 | Molecular Pain

Figure 4

From: Tumor necrosis factor-alpha (TNF-α) enhances functional thermal and chemical responses of TRP cation channels in human synoviocytes

Figure 4

TNF-α modulation of the SW982 synoviocyte [Ca2+ ] i response to 36°C. A and B: Representative calcium traces recorded from (A) control (vehicle treated) synoviocytes and (B) TNF-α (1 ng/ml, 8 hr) pretreated cells. (C) Peak and average calcium response in control (white bars, n = 7) or TNF-α (1 ng/ml) treated synoviocytes. The TNF-α was added to the incubation media for 4 hr (n = 4 trials), 8 hr (n = 5 trials), 12 hr (n = 5 trials), or 16 hr (n = 4 trials) before the experiment. * indicates a statistically significant difference (p < 0.05) tested by ANOVA on ranks.

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Molecular Pain

ISSN: 1744-8069

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