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Figure 4 | Molecular Pain

Figure 4

From: Modulation of transient receptor potential vanilloid 4-mediated membrane currents and synaptic transmission by protein kinase C

Figure 4

Enhancement of TRPV4-mediated single-channel current activity by PKC. A. Single-channel currents activated by 4α-PDD (1 μM) recorded at + 60 mV from a cell-attached patch on TRPV4 transfected HEK 293T cells before and after PDBu incubation. The traces are shown at higher time resolution below and the amplitude histograms are shown on the right. B. 4α-PDD-induced single-channel currents recorded at – 60 mV before and after PDBu incubation. The traces are shown at a higher time resolution below and the amplitude histograms are shown on the right.

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