Figure 2

Thalamocingulate responses during formalin injection to the hind paw (A, red asterisk). Mulichannel unit activities and local field potentials were recorded from the MITN (B) and ACC (C) respectively. D. Aligned multichannel thalamic unit activities and ACC spontaneous local field potentials showing that bursting activity and local field potential in both structures is correlated. E. The initial time of bursting (arrow heads aligned at the red lines) of MITN unit activities were aligned. Current source density profile across the cingulate cortical layer was calculated from the local field potentials. Abbreviations: MDM, mediodorsal thalamic nucleus, Pv, paraventricular thalamic nucleus, Hb, habenular nucleus.