Figure 4

PPF and tetanic potentiation of the ACC evoked by stimulation of the thalamus or the contralateral corpus callosum (CC). A. Schematic diagram showing stimulation and recording sites in an ACC slice model. B. Example traces of EPSPs evoked by different inputs at varying paired pulse intervals (50-800 ms). C. A greater paired-pulse potentiation ratio (second EPSP/first EPSP) at the 50- and 100-ms intervals was observed with stimulation in the thalamus than in the contralateral CC (*P < 0.01 vs stimulation in contralateral CC). Data are means ± SEM. D. Example traces of tetanic potentiation in the ACC evoked by stimulation of the thalamus, or contralateral CC. E. Potentiated responses (Max/Control EPSP) were greater with thalamic stimulation than with contralateral CC stimulation, at 20 and 50 Hz (*P < 0.01 vs contralateral CC stimulation). Data are means ± SEM (Modified from 46).