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Figure 7 | Molecular Pain

Figure 7

From: Short-term synaptic plasticity in the nociceptive thalamic-anterior cingulate pathway

Figure 7

Responses in the ACC evoked by paired-pulse stimulation. A. The part of ACC in which the half-maximal response for the first field potential (dark gray area) and second field potentials (light gray area) was determined following electrical stimulation in the deep layers (BSE, bipolar stimulating electrodes). B. The evoked-field potentials (EFP; either field action potential-fAP or field postsynaptic potential-fPSP) were recorded and fPSPs totally abolished in the presence of Ca2+-free aCSF. C. Effects of CNQX (15 μM) and APV (30 μM) on EFP. D. Frequency-response dependence in the presence of low external [Ca2+] (1 mM) aCSF and high [Ca2+] (3 mM) aCSF. E. Relationship between the ratio of max/control, min/control and frequency under the different external [Ca2+] concentrations (Modified from 66).

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