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Table 1 Effects of bupivacaine microspheres and RTX on nociception, motor function, and proprioception.

From: Large A-fiber activity is required for microglial proliferation and p38 MAPK activation in the spinal cord: different effects of resiniferatoxin and bupivacaine on spinal microglial changes after spared nerve injury

  Hop Flip Pinch (sural) Pinch (saphenous)
  Normal Blocked Normal Blocked Normal Blocked Normal Blocked
Control (n = 6) 6 0 6 0 6 0 6 0
RTX only (n = 5) 5 0 5 0 5 0 5 0
Bub only (n = 3) 0 3 0 3 0 3 3 0
SNI+vehicle (n = 10) 0 10 0 10 10 0 10 0
SNI+RTX (n = 9) 0 9 0 9 9 0 9 0
SNI+Bup (n = 5) 0 5 0 5 0 5 5 0
  1. Nociceptive response was tested by pinching the hind paws in the sural and saphenous nerve territories. Proprioception and motor function were examined by checking hopping and flipping responses.