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Table 1 Effects of bupivacaine microspheres and RTX on nociception, motor function, and proprioception.

From: Large A-fiber activity is required for microglial proliferation and p38 MAPK activation in the spinal cord: different effects of resiniferatoxin and bupivacaine on spinal microglial changes after spared nerve injury

 

Hop

Flip

Pinch (sural)

Pinch (saphenous)

 

Normal

Blocked

Normal

Blocked

Normal

Blocked

Normal

Blocked

Control (n = 6)

6

0

6

0

6

0

6

0

RTX only (n = 5)

5

0

5

0

5

0

5

0

Bub only (n = 3)

0

3

0

3

0

3

3

0

SNI+vehicle (n = 10)

0

10

0

10

10

0

10

0

SNI+RTX (n = 9)

0

9

0

9

9

0

9

0

SNI+Bup (n = 5)

0

5

0

5

0

5

5

0

  1. Nociceptive response was tested by pinching the hind paws in the sural and saphenous nerve territories. Proprioception and motor function were examined by checking hopping and flipping responses.