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Figure 2 | Molecular Pain

Figure 2

From: NMDA receptor subunit expression and PAR2 receptor activation in colospinal afferent neurons (CANs) during inflammation induced visceral hypersensitivity

Figure 2

Expression of the TRPV1 receptor is eliminated following treatment with RTX. Photomicrographs of DiI and TRPV1 expression in control(a') and RTX(a") lesioned rats in submucosal plexus of the colon. RTX results in a decrease in the expression of TRPV1 labeling in the colon. Photomicrographs that show a decrease in both DiI and TRPV1 expression in lumbosacral DRG neurons(b") as compared to controls(b'). (c) Immunohistochemical characterization of CANs following RTX lesioning showed no change in peptide and receptor expression as compared to controls. RTX results in a decrease in the expression of TRPV1 labeling in thoracolumbar DRG neurons (e). Scale bars = 20 μm(a) and 50 μm(b, e).

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Molecular Pain

ISSN: 1744-8069

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