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Figure 4 | Molecular Pain

Figure 4

From: Nociception-induced spatial and temporal plasticity of synaptic connection and function in the hippocampal formation of rats: a multi-electrode array recording

Figure 4

Pharmacological identification of the perforant path-induced network field potentials on the hippocampal slices. A and C, showing pooled data from 7 similar experiments with strong inhibition of field potentials by either bath application of TTX (0.5 μM and 1 μM) or perfusion with high magnesium-low calcium solution (CaCl2, 0.25 mM, MgSO4, 4.0 mM). All values were normalized as a percentage of baseline. B and D, showing representative raw traces of positive- (left) and negative-going (right) field potentials recorded in the dentate gyrus and CA1 area before treatment, 10 min after TTX infusion (B) or ionic substitution (D), and the washout end. Vertical scale indicates amplitude of the potentials, while horizontal scale indicates time sweep for both B and D. **P < 0.01 vs. baseline. Error bars: ± S.E.M.

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Molecular Pain

ISSN: 1744-8069

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