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Figure 5 | Molecular Pain

Figure 5

From: Enhanced pre-synaptic glutamate release in deep-dorsal horn contributes to calcium channel alpha-2-delta-1 protein-mediated spinal sensitization and behavioral hypersensitivity

Figure 5

Similar excitability to high intensity electrical stimulation between WT and TG wide-dynamic-range neurons. Extracellular recordings were performed blindly to record dorsal horn single WDR neuron activity in response to C-fiber strength electrical stimulation applied to the receptive fields over the hindpaw of the WT and TG mice. Numbers of spikes from each neuron were pooled and the data are presented as the means ± SEM from n = 10 in each group. C – C-fiber responses. PD – post discharge.

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