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Table 1 Properties of mIPSCs in mouse SDH and DDH neurons

From: Different forms of glycine- and GABAA-receptor mediated inhibitory synaptic transmission in mouse superficial and deep dorsal horn neurons

mIPSC properties   Channel properties
mIPSC
type 		Region Amplitude
(pA) 		Rise time
(ms) 		Decay time
(ms) 		Frequency
(Hz) 		Chargeδ
(pA.ms) 		n Conductance
(pS) 		Open probability
(P o ) 		Channel
number 		n
Glycine SDH 37.1 ± 3.9* 0.85 ± 0.07 8.5 ± 0.8* 0.15 ± 0.03* 364.5 ± 57.7 25 54.3 ± 1.6 .97 ± 0.01 10.3 ± 0.5* 8
  DDH 64.7 ± 5.0 0.85 ± 0.04 5.5 ± 0.3 0.72 ± 0.13 456.6 ± 39.9 25 55.7 ± 1.8 99 ± 0.01 19.0 ± 5.3 11
GABA A SDH 25.6 ± 2.4 1.97 ± 0.18* 23.0 ± 3.2* 0.21 ± 0.08 717.3 ± 75.5* 14 22.7 ± 1.7 0.76 ± 0.04* 18.5 ± 1.6* 8
  DDH 25.3 ± 2.0 1.49 ± 0.10 18.9 ± 1.6 0.18 ± 0.04 486.3 ± 52.4 18 22.4 ± 2.0 0.94 ± 0.02 12.9 ± 1.0 11
  1. * indicates significant differences for SDH and DDH values
  2. δ mIPSC charge calculated in Axograph using averages for peak amplitude, rise- and decay times
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Molecular Pain

ISSN: 1744-8069

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