Loss of neuronal pNF-H immunoreactivity induced by oxaliplatin in rat DRG tissue. Photomicrographs (A, B; magnification: 100×) and cell body size frequency histograms (C, D) of pNF-H-immunoreactive L5 DRG neurons from rats treated with the control vehicle (A, C) or oxaliplatin (B, D). Oxaliplatin reduced pNF-H immunostaining of neuronal cell bodies (↑) without changing pNF-H immunoreactivity of ganglionic nerve fibers (←). Cell body size frequency histograms of pNF-H-immunoreactive neurons were altered by oxaliplatin. Bars represent the mean and standard error of the mean for 4 animals.