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Figure 4 | Molecular Pain

Figure 4

From: Oxaliplatin-induced loss of phosphorylated heavy neurofilament subunit neuronal immunoreactivity in rat DRG tissue

Figure 4

Comparative effect of anticancer drugs on neuronal pNF-H immunoreactivity. DRG were analysed after multiple-dose treatment with maximally tolerated doses of oxaliplatin (Oxal; 1.85 mg/kg/dose twice per week for 8 weeks), cisplatin (Cispl; 1 mg/kg/dose twice per week per 8 weeks), carboplatin (Carb; 8 mg/kg/dose twice per week per 8 weeks) and paclitaxel (Pacl; 12.5 mg/kg/dose once per week for 9 weeks). Bars represent the mean and standard deviation of 3 to 6 animals, * P < 0.01.

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