Figure 2
Galanin is up-regulated and Scn11a is down-regulated following spinal nerve ligation (SNL). Gene expression, plotted in relation to that of the stable housekeeping gene Gapdh, was assessed using TaqMan analysis 3 days following L5 SNL. Expression profiles for both genes are shown for individual mice of the A, C3H strain (labelled C3Ha-o) and B, C58 strain (labelled C58a-r). Arrows in B, indicate two outlier mice in which expression levels of both Galanin and Scn11a correspond to sham operated animals, suggesting that spinal nerve injury had not been carried out adequately.