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Table 1 Quantification of leukocyte subpopulations and of opioid-containing leukocytes in inflamed paws following intraplantar delivery of POMC-MIDGE-NLS.

From: Peripheral non-viral MIDGE vector-driven delivery of β-endorphin in inflammatory pain

Treatment Total cell counts (× 103) per paw
  Granulocytes Monocytes/
macrophages
T cells Opioid cells
control MIDGE-NLS 44 ± 13 823 ± 132 62 ± 12 403 ± 65
50 μg     
POMC-MIDGE-NLS     
25 μg 56 ± 19 566 ± 89 60 ± 14 262 ± 42
50 μg 92 ± 16 633 ± 56 51 ± 6 358 ± 38
100 μg 99 ± 40 691 ± 159 50 ± 11 379 ± 91
  1. Leukocyte counts were determined by flow cytometry. There were no significant differences between control MIDGE-NLS and POMC-MIDGE-NLS (p > 0.05, one-way ANOVA).