Table 1 Quantification of leukocyte subpopulations and of opioid-containing leukocytes in inflamed paws following intraplantar delivery of POMC-MIDGE-NLS.
From: Peripheral non-viral MIDGE vector-driven delivery of β-endorphin in inflammatory pain
Treatment | Total cell counts (× 103) per paw | |||
|---|---|---|---|---|
Granulocytes | Monocytes/ macrophages | T cells | Opioid cells | |
control MIDGE-NLS | 44 ± 13 | 823 ± 132 | 62 ± 12 | 403 ± 65 |
50 μg | ||||
POMC-MIDGE-NLS | ||||
25 μg | 56 ± 19 | 566 ± 89 | 60 ± 14 | 262 ± 42 |
50 μg | 92 ± 16 | 633 ± 56 | 51 ± 6 | 358 ± 38 |
100 μg | 99 ± 40 | 691 ± 159 | 50 ± 11 | 379 ± 91 |