Changes of action potential properties of IM pyramidal neurons in the ACC after neuropathic pain. A-C, Examples of APs generated from RS, IM, and IB neurons. All responses elicited in response to a 400 ms depolarizing current pulse of appropriate suprathreshold magnitude. Current records omitted for clarity. A, APs of neurons from non-operated mice; B, APs of neurons from sham-operated mice; C, APs of neurons from neuropathic pain mice; D-F, Histograms for data from RS (control, n = 20; neuropathic, n = 13), IM (control, n = 36; neuropathic, n = 29), and IB (control, n = 25; neuropathic, n = 19) neurons reflect rheobase, AP threshold and half width from control mice (non-operated and sham-operated) and neuropathic pain mice (P > 0.05, Student t-test). All values are given as the mean ± SEM.