The levels of immunoreactive kinins were significantly lower at the third hour compared to the first 2 hours. There was no significant difference between the placebo and ketorolac treatment groups. Fig. (1a) shows the levels of B2 receptor ligands (BK and KD) and Fig. (1b) shows the levels of B1 receptor ligands (des-Arg9-BK and des-Arg10-KD). Concentrations of immunoreactive kinins (pg/ml) were transformed into Ln (X+1), which is shown here. For details, please refer to the methods section. Figures show the levels measured at the left side. The right side showed similar results. Data are presented as mean ± SEM; *indicated p < 0.05, 3 way ANOVA.