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Table 1 Gene expression of kinin receptors, TRPV1 and NFκB:

From: Kinin B1 receptors contributes to acute pain following minor surgery in humans

  Placebo Ketorolac
  Pre-surgery
(Average ΔCt)
Post-surgery
(Average ΔCt)
Fold change*
(P value)
Pre-surgery
(Average ΔCt)
Post-surgery
(Average ΔCt)
Fold change*
(P value)
B 1 receptor
(BDKRB1)
17.4 ± 3.6 16.2 ± 3.6 2.5 ± 0.9
(p < 0.0001)
18.6 ± 3.4 17.4 ± 3.5 2.4 ± 0.8
(p < 0.0001)
B 2 receptor
(BDKRB2)
14.8 ± 3.0 13.8 ± 2.9 2.0 ± 0.6
(p < 0.0001)
15.6 ± 2.7 14.7 ± 2.7 1.9 ± 0.5
(p < 0.0001)
NFκB 17.3 ± 0.6 17.0 ± 0.4 1.3 ± 1.2
(p = 0.027)
17.3 ± 0.5 17.0 ± 0.7 1.4 ± 0.8
(p = 0.042)
TRPV1 18.8 ± 2.9 19.8 ± 2.7 -2.2 ± 0.9
(p < 0.0001)
19.5 ± 2.7 20.7 ± 2.9 -2.6 ± 1.1
(p < 0.0001)
  1. Data are presented as mean ± S.D.; n = 13-15 per group.
  2. *Fold change is calculated as 2-ΔΔCt, Average ΔCt is the normalized cycle threshold in reference to the endogenous control (18S rRNA). Data were analyzed using paired t test.