Table 1 Gene expression of kinin receptors, TRPV1 and NFκB:
From: Kinin B1 receptors contributes to acute pain following minor surgery in humans
| Placebo | Ketorolac | |||||
|---|---|---|---|---|---|---|
|
Pre-surgery
(Average ΔCt) |
Post-surgery
(Average ΔCt) |
Fold change*
(P value) |
Pre-surgery
(Average ΔCt) |
Post-surgery
(Average ΔCt) |
Fold change*
(P value) | |
|
B
1
receptor
(BDKRB1) | 17.4 ± 3.6 | 16.2 ± 3.6 |
2.5 ± 0.9 (p < 0.0001) | 18.6 ± 3.4 | 17.4 ± 3.5 |
2.4 ± 0.8 (p < 0.0001) |
|
B
2
receptor
(BDKRB2) | 14.8 ± 3.0 | 13.8 ± 2.9 |
2.0 ± 0.6 (p < 0.0001) | 15.6 ± 2.7 | 14.7 ± 2.7 |
1.9 ± 0.5 (p < 0.0001) |
| NFκB | 17.3 ± 0.6 | 17.0 ± 0.4 |
1.3 ± 1.2 (p = 0.027) | 17.3 ± 0.5 | 17.0 ± 0.7 |
1.4 ± 0.8 (p = 0.042) |
| TRPV1 | 18.8 ± 2.9 | 19.8 ± 2.7 |
-2.2 ± 0.9 (p < 0.0001) | 19.5 ± 2.7 | 20.7 ± 2.9 |
-2.6 ± 1.1 (p < 0.0001) |
