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Figure 2 | Molecular Pain

Figure 2

From: Nitric oxide synthase modulates CFA-induced thermal hyperalgesia through cytokine regulation in mice

Figure 2

Relative gene expression of nNOS (A), iNOS (B) and eNOS (C) in the ipsilateral plantar skin in mice receiving CFA compared to control mice receiving NS (NS + CFA vs NS + NS). NNOS (A) and eNOS (C) gene expression was increased at 6 h (***P < 0.001), followed by a rapid decline to baseline levels at 16 and 24 h, after CFA. INOS gene expression was increased at 6 h, and peaked at 24 h, after CFA (B, **P < 0.01 and ***P < 0.001). At each time point n = 4.

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