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Figure 7 | Molecular Pain

Figure 7

From: TRPA1 modulation of spontaneous and mechanically evoked firing of spinal neurons in uninjured, osteoarthritic, and inflamed rats

Figure 7

Effects of A-967079 (30 μmol/kg, i.v.) on single WDR neurons recorded from either (A) an OA-sham or (B) an OA rat. In both cases, A-967079 reduced the evoked responses of WDR neurons following high-intensity stimulation (300 g von Frey for 10 s), but did not change the spontaneous activity. R = gentle manual rubbing of the knee joint, VF = 300-g von Frey hair stimulation of the knee, char = characterization period.

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