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Figure 3 | Molecular Pain

Figure 3

From: Transient Receptor Potential Vanilloid 1 is essential for cisplatin-induced heat hyperalgesia in mice

Figure 3

TRPV1 immunoreactivity following platinum drug treatment. Representative sections of TRPV1 immunoreactivity of TG neurons from (A) vehicle-, (B) cisplatin-, and (C) oxaliplatin- treated wild-type mice after 3 weeks treatment. Arrows indicate examples of labeled neuronal profiles. (D) Frequency histogram showing the percentage of labeled TRPV1 profiles in each group. Quantitative analysis of the proportion of TRPV1 immunopositive TG neuronal profiles stained as shown in (A, B, and C) from vehicle-, cisplatin-, and oxaliplatin-treated C57BL6J wild-type mice after 3 weeks treatment. Data represents mean ± SD, n = 4 mice/group, (*P < 0.05, two-way ANOVA, Scale bar = 25 μm).

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