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Figure 1 | Molecular Pain

Figure 1

From: Cannabinoid-mediated modulation of neuropathic pain and microglial accumulation in a model of murine type I diabetic peripheral neuropathic pain

Figure 1

Timelines for experiments performed. Experiment 1 examined the natural history of nociception and microglial presence over 8 months of diabetes. Experiment 2 examined the intranasal and intraperitonel delivery of CB2 agonists/antagonists either at diabetes initiation or after diabetic peripheral neuropathy-mediated neuropathic pain has initiated. Experiment 3 examined the intranasal and intraperitonel delivery of CB1 agonists/antagonists (as well as one CB1 and CB2 agonist) either at diabetes initiation or after diabetic peripheral neuropathy-mediated neuropathic pain has initiated.

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