Figure 2

Exogenous agonist-induced currents inhibited by xenon. A - Representative traces showing NMDA (50 μM, 30 s)-induced outward currents at HP = +40 mV, which were reversibly reduced by xenon (50%). Drug application is marked with bars. B - Xenon decreased the amplitude and integrated area of NMDA-induced currents in lamina II neurons (n = 8). *P < 0.05 compared with control. C - AMPA (10 μM, 30 s)-induced inward currents at HP = -70 mV, which were reversibly reduced by xenon (50%). D - Xenon decreased the amplitude and integrated area of NMDA-induced currents in lamina II neurons (n = 7). *P < 0.05 compared with control.