Figure 3
From: Xenon inhibits excitatory but not inhibitory transmission in rat spinal cord dorsal horn neurons
Xenon decreased mEPSC amplitude, but not mEPSC frequency. A - Two-scale traces of mEPSC recorded at HP = -70 mV in the presence of tetrodotoxin (1 μM) before, during and after xenon application. B - The effect of xenon on miniature excitatory postsynaptic current (mEPSC) amplitude (n = 16) and frequency (n = 16). *P < 0.05 compared with control. C - Cumulative histograms of mEPSC amplitude (left) and inter-event intervals (right) from a representative neuron showing the shift to the left of mEPSC amplitude under xenon exposure. Control trace was calculated from 470 events and xenon trace was calculated from 490 events.