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Figure 1 | Molecular Pain

Figure 1

From: Differential adeno-associated virus mediated gene transfer to sensory neurons following intrathecal delivery by direct lumbar puncture

Figure 1

Mannitol enhances GFP expression in mouse spinal cord and DRG. Sections are from mice perfused six weeks after i.t. injection of rAAV5-GFP with or without intravenous mannitol pretreatment. A) GFP immunoreactivity (-ir) in the spinal cord of a mannitol-pretreated mouse. B) GFP-ir in spinal cord of a saline-pretreated mouse. C) GFP-ir in L4 DRG of a mannitol-pretreated mouse. D) Mannitol pretreatment significantly enhances transduction of lumbar DRG neurons when compared to saline pretreatment; Mann-Whitney, U05(1),3,3 = 9, p = 0.05.

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Molecular Pain

ISSN: 1744-8069

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