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Table 2 Impact of COMT genotype on fMRI BOLD activation

From: The val158met polymorphism of human catechol-O-methyltransferase (COMT) affects anterior cingulate cortex activation in response to painful laser stimulation

Region of Interest Genotype (df = 1)
  Met/Met
(Mean Z value/SD)
Val carriers
(Mean Z value/SD)
F p
ACC 1.69/1.75 0.55/1.05 9.447 0.003
Insula 2.29/1.88 1.40/1.08 5.136 0.027
parietal operculum (containing S2) 2.13/1.75 1.36/0.94 4.677 0.035
Amygdalae 1.09/1.48 0.52/0.85 3.507 0.066
  1. Analyses of variance (ANOVAs) with genotype as factor and mean Z values in regions of interest as dependent variables.
  2. df = degrees of freedom; ACC = anterior cingulate cortex; S2 = secondary somatosensory cortex; SD = standard deviation